• Blog
  • About
  • Partners
  • Contact
  • Fundraise
Give Now »
Young Survival Coalition logo
    • Learn
      • About Breast Cancer
        • Breast Cancer 101
        • Breast Cancer Statistics
        • Breast Cancer Risk Factors
        • FAQs
      • Living With Breast Cancer
        • Understanding Treatment
        • Quality of Life
        • Fertility and Family Planning
        • Practical Concerns
        • Clinical Trials
      • Metastatic Breast Cancer
        • Metastatic Breast Cancer Diagnosis
        • Metastatic Breast Cancer Treatment
        • Living with Metastatic Breast Cancer
        • Metastatic Clinical Trial Search
        • Metastatic Breast Cancer Resources
      • Resources and Tools
        • Search for Resources
        • Audio/Video Library
        • Educational Materials
        • Partner Resources
      • Co-Survivors
        • Self-Care
        • How To Help
        • Co-Survivor
          Community
      • Research
        • Research Agenda
        • Position Papers
        • Metastatic Survey
      • En Español
    • Connect
      • Find Support Online
        • Virtual Hangouts
        • Private Facebook Groups
      • Meet In Person
        • Local Meetups
        • Conferences
      • Talk One-On-One
    • Get Involved
      • Volunteer
      • Attend A Conference
      • Be An Advocate
      • Fundraise or Host an Event
      • Ride in Tour de Pink
      • Pledge Your Birthday
      • Upcoming Events
      • #TitCheck BCA Campaign
    • Be Inspired
    • Donate
      • Make a Donation
      • Fundraise for YSC
      • All Ways to Give
Young Survival Coalition logo

Mobile Menu

Young Survival Coalition logo
  • Blog
  • About
  • Partners
  • Contact
  • Fundraise
  • Learn
    • About Breast Cancer
      • Breast Cancer 101
      • Breast Cancer Statistics
      • Breast Cancer Risk Factors
      • FAQs
    • Living With Breast Cancer
      • Understanding Treatment
      • Quality of Life
      • Fertility and Family Planning
      • Practical Concerns
      • Clinical Trials
    • Metastatic Breast Cancer
      • Metastatic Breast Cancer Diagnosis
      • Metastatic Breast Cancer Treatment
      • Living with Metastatic Breast Cancer
      • Metastatic Clinical Trial Search
      • Metastatic Breast Cancer Resources
    • Resources and Tools
      • Search for Resources
      • Audio/Video Library
      • Educational Materials
      • Partner Resources
    • Co-Survivors
      • Self-Care
      • How To Help
      • Co-Survivor
        Community
    • Research
      • Research Agenda
      • Position Papers
      • Metastatic Survey
    • En Español
  • Connect
    • Find Support Online
      • Virtual Hangouts
      • Private Facebook Groups
    • Meet In Person
      • Local Meetups
      • Conferences
    • Talk One-On-One
  • Get Involved
    • Volunteer
    • Attend A Conference
    • Be An Advocate
    • Fundraise or Host an Event
    • Ride in Tour de Pink
    • Pledge Your Birthday
    • Upcoming Events
    • #TitCheck BCA Campaign
  • Be Inspired
  • Donate
    • Make a Donation
    • Fundraise for YSC
    • All Ways to Give

Menu: Research Think Tank Fertility Work Group

  • YSC Research Agenda
  • Clinical Trials
  • Position Papers
  • Metastatic Survey Results
  • Newly Diagnosed Navigator
  • Metastatic Navigator
  • Post-Treatment Navigator
  • Long Term Navigator
Share

Research Think Tank Fertility

The Research Think Tank (RTT) Fertility Work Group focused on unanswered questions relating to a young woman maintaining her fertility throughout breast cancer treatment. It also addressed the use and safety of fertility preservation.

The group was composed of advocates:

  • Anna Cluxton (chair)
  • Linda Dias
  • Penina Seidman
  • Kristin Smith

As well as physicians/researchers:

  • Dr. Francesca Duncan
  • Dr. Jacqueline Gutmann
  • Dr. Kutluk Oktay
  • Dr. Malcolm Pike
  • Dr. Irene Su

Research Priorities

Two of the 19 research priorities recommended by the RTT focused on fertility. Below, we list the priority, indicate any progress made since the RTT and list any open trials of which we are aware related to or focusing on these research priorities.

What are fertility options for young women diagnosed with breast cancer? How likely are they to result in healthy children? What is their impact on long-term outcomes in younger breast cancer patients?

Progress made: Work In Progress


Recent research updates:

Use of assisted reproductive technology in breast cancer survivors does not appear to increase risk of recurrence/relapse; however, a larger confirmatory study is needed. Read More

Current research initiatives/studies:

POSITIVE Trial will capture data pregnancy rates and outcomes on ER+ breast cancer, including the use of assisted reproductive technology.

RCT of Fixed vs. Titrated Letrozole in Breast Cancer Patients undergoing In Vitro Fertilization to determine efficacy of blocking estrogen production during ovarian stimulation.


Which breast cancer treatments cause infertility? How do additional risk factors such as age and ovarian reserve modify risks of infertility from cancer treatment? Can drugs be developed that lessen the impact on fertility?

Progress made: Ongoing


Recent research updates:

Use of ovarian suppression during chemotherapy appears to protect against ovarian failure. Read More

Ovarian suppression during chemotherapy appears to increase pregnancy rate of breast cancer survivors. Read More

Current research initiatives/studies:

Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma to examine how cancer treatment affects the ovaries and ability to have children.  

Predictors of Ovarian Insufficiency in Young Breast Cancer Patients (POISE) is ongoing, but closed to recruitment. This study will identify pre-chemotherapy markers that can predict ovarian failure and characterize ovarian failure after chemotherapy.

Learn More

If you believe we are missing a crucial piece of research or have not included a research study which should be here, please contact us!

Read about the work of the RTT Pregnancy Work Group.

Read our Research Agenda and white paper on the RTT process.

Related Topics

Research Think Tank Metastasis Work Group

Research Think Tank Metastasis Work Group

The Research Think Tank (RTT) Metastasis Work Group focused on the unique issues and concerns of young women diagnosed with metastatic breast cancer.
Research Think Tank Pregnancy Work Group

Research Think Tank Pregnancy Work Group

The Research Think Tank (RTT) Pregnancy Work Group focused on unanswered questions relating to all aspects of breast cancer and pregnancy. These included breast cancer treatment during pregnancy, postpartum breast cancer and the safety of pregnancy after breast cancer.
Research Think Tank Quality of Life Work Group

Research Think Tank Quality of Life Work Group

The Research Think Tank (RTT) Quality of Life Work Group focused on unanswered questions about a young woman's life and side effects during and after breast cancer treatment.
Research Think Tank Risk Factors Work Group

Research Think Tank Risk Factors Work Group

The Research Think Tank (RTT) Risk Factors Work Group focused on unanswered questions about what increases the risk of young women developing breast cancer. These risk factors likely differ from what causes the disease in older women.
Research Think Tank Treatment Work Group

Research Think Tank Treatment Work Group

The Research Think Tank (RTT) Treatment Work Group focused on unanswered questions about the most optimal treatment of breast cancer in a young woman and how that treatment may differ from that given to an older woman.

Search for Resources

Audio & Video Library

Educational Materials

Conferences

  • About YSC
  • FAQs
  • Careers
  • Media Center
  • Contact

Young Survival Coalition is a qualified 501(c)(3) tax exempt nonprofit organization dedicated to all young breast cancer survivors and their co-survivor support networks. YSC's EIN is 13-4057685.


405 Lexington Avenue, 26th Floor | New York, NY 10174 | phone: 877.972.1011 | fax: 646.257.3030

© 1998-2023 Young Survival Coalition. All rights reserved. Privacy Policy | Terms of Service | website design by efelle