What are aromatase inhibitors?
Aromatase inhibitors are the standard of care in hormone receptor positive post-menopausal women. They work by blocking the enzyme aromatase, which turns the hormone androgen into small amounts of estrogen in the body. This ensures that less estrogen is available to stimulate the growth of hormone receptor positive breast cancer cells. Some women who experience early menopause may be temporarily put on tamoxifen for a year or two until it is certain that menopause was not temporary before switching to an aromatase inhibitor. Some women choose to go into surgical or medically induced menopause so they can take aromatase inhibitors.