Breast Cancer In Young Women

Managing Your Life: Metastatic Treatment

If you’ve had a diagnosis of metastatic breast cancer, you might feel scared and overwhelmed, perhaps concerned about the prospects of treatment. However, you should know that you have reasons to be hopeful. Doctors treat metastatic breast cancer as a chronic disease, managing the cancer for as long as possible with hopes of remission.


Treatment can make it possible for you to lead years of a fulfilling life. Some women far outlive their prognoses and can manage their diseases with a high quality of life for many years. A small percentage of women with metastatic breast cancer go into full remission after treatment.

For more information on specific breast-cancer treatments, see our pages on chemotherapy, radiation and targeted therapies.

Testing

Your diagnosis and treatment will call for a lot of tests. The first tests, during diagnosis, find the location of metastases. Read more about diagnostic tests here.

Doctors will use later tests to see how well your treatment is working, if it is shrinking the cancer or keeping it from growing. Additionally, doctors will ask about your symptoms—treatment should also manage pain, other symptoms and treatment side-effects.

A lot of the valuable information will come from your pathology report. This in-depth description of your cancer may seem intimidating because of all the medical terminology. To better understand it, please visit our pathology page. Also, remember that a metastatic recurrence may not have the same pathology as your original cancer. Talk to your doctor about this possibility and discuss having another biopsy to learn more about your new pathology**.

Lines of Treatment

Understanding what to expect during your treatment can make it feel more manageable. In general, doctors will try one therapy after another, pursuing each one as long as it works. If one course of therapy stops working, you can turn to others to stabilize the disease. Doctors refer to each new treatment as a “line of treatment.”

By closely monitoring treatments and changing them when necessary, doctors can often stabilize your cancer for a long time. For this reason, some doctors view treating metastatic breast cancer as similar to treating a chronic disease.

Clinical Trials

Be sure to ask your doctor if you might qualify for any clinical trials. For metastatic women, trials should be considered as a first resort, not a last one. Some clinical trials may not allow women with a lot of pre-treatment to enroll. Talk to your doctor about your eligibility.

These trials, important sources of information for researchers, also give you the opportunity to try new treatments. They may offer an improvement over the current, standard treatments. One doctor may have access to clinical trials that another doesn’t, so look around. Learn more about clinical trials.

RSS: Metastatic Breast Cancer Clinical Trials

Studies found on ClinicalTrials.gov by a search of: metastatic breast cancer | updated in the last 30 days


Breast Cancer Molecular Analysis Protocol
Condition:   Metastatic Breast Cancer
Intervention:   Procedure: Core Biopsy
Sponsors:   Yale University;   Yale University;   Foundation Medicine
Recruiting - verified May 2013

Mon, 13 May 2013 12:00:00 EDT

Management of Metastatic Breast Cancer in Clinical Practice - Retrospective Study
Condition:   Metastatic Breast Cancer
Intervention:  
Sponsors:   AstraZeneca;   AstraZeneca
Active, not recruiting - verified April 2013

Mon, 22 Oct 2012 12:00:00 EDT

Investigating Safety, Tolerability and Efficacy of AZD5363 When Combined With Paclitaxel in Breast Cancer Patients
Conditions:   Advanced or Metastatic Breast Cancer,;   ER+ve Advanced or Metastatic Breast Cancer.
Interventions:   Drug: AZD5363 when combined with weekly paclitaxel.;   Drug: AZD5363 when combined with weekly paclitaxel.;   Drug: AZD5363when combined with weekly paclitaxel.;   Drug: A placebo in combination with weekly paclitaxel.
Sponsors:   AstraZeneca;   AstraZeneca
Recruiting - verified May 2013

Thu, 10 May 2012 12:00:00 EDT

AZD2014 and Fulvestrant in Patients With ER+ Advanced Metastatic Breast Cancer
Condition:   Advanced Metastatic Breast Cancer
Interventions:   Drug: AZD2014;   Drug: Fulvestrant
Sponsors:   AstraZeneca;   AstraZeneca
Recruiting - verified April 2013

Wed, 28 Mar 2012 12:00:00 EDT

Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer
Conditions:   Breast Cancer;   Metastatic Breast Cancer;   Stage IV Breast Cancer
Interventions:   Drug: Ixabepilone;   Drug: Capecitabine;   Drug: Motesanib
Sponsors:   Thomas Jefferson University;   Thomas Jefferson University;   Susan G. Komen Breast Cancer Foundation;   Amgen
Not yet recruiting - verified May 2013

Wed, 04 May 2011 12:00:00 EDT

Study of BKM120 or BEZ235 and Capecitabine in Patients With Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Interventions:   Drug: BMK120;   Drug: Capecitabine;   Drug: BEZ235;   Drug: Trastuzumab;   Drug: Lapatinib
Sponsors:   UNC Lineberger Comprehensive Cancer Center;   UNC Lineberger Comprehensive Cancer Center;   Novartis Pharmaceuticals
Recruiting - verified May 2013

Thu, 17 Feb 2011 12:00:00 EST

A Study of Trastuzumab-MCC-DM1 in Patients With HER2- Positive Locally Advanced or Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Intervention:   Drug: trastuzumab-MCC-DM1
Sponsors:   Genentech;   Genentech
Approved for marketing - verified May 2013

Fri, 07 May 2010 12:00:00 EDT

ABT-888 and Temozolomide for Metastatic Breast Cancer and BRCA1/2 Breast Cancer
Conditions:   Breast Cancer;   Metastatic Breast Cancer;   BRCA1 or BRCA2 Associated Breast Cancer
Interventions:   Drug: ABT-888;   Drug: temozolomide
Sponsors:   Massachusetts General Hospital;   Steven Isakoff, MD, PhD;   Dana-Farber Cancer Institute;   Beth Israel Deaconess Medical Center;   Abbott
Active, not recruiting - verified April 2013

Thu, 05 Nov 2009 12:00:00 EST

Cyclosporine A in Combination With Nab-Paclitaxel in Patients With Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Interventions:   Drug: Cyclosporins;   Drug: nab-paclitaxel
Sponsors:   Northwestern University;   Northwestern University;   Avon Foundation
Active, not recruiting - verified April 2013

Tue, 22 Sep 2009 12:00:00 EDT

Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response
Condition:   Breast Cancer
Interventions:   Drug: Cisplatin;   Drug: carboplatin
Sponsors:   Massachusetts General Hospital;   Massachusetts General Hospital;   Beth Israel Deaconess Medical Center;   Dana-Farber Cancer Institute;   North Shore Medical Center
Active, not recruiting - verified April 2013

Tue, 05 Jun 2007 12:00:00 EDT

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