Breast Cancer In Young Women

Managing Your Life: Metastatic Treatment

If you’ve had a diagnosis of metastatic breast cancer, you might feel scared and overwhelmed, perhaps concerned about the prospects of treatment. However, you should know that you have reasons to be hopeful. Doctors treat metastatic breast cancer as a chronic disease, managing the cancer for as long as possible with hopes of remission.


Treatment can make it possible for you to lead years of a fulfilling life. Some women far outlive their prognoses and can manage their diseases with a high quality of life for many years. A small percentage of women with metastatic breast cancer go into full remission after treatment.

For more information on specific breast-cancer treatments, see our pages on chemotherapy, radiation and targeted therapies.

Testing

Your diagnosis and treatment will call for a lot of tests. The first tests, during diagnosis, find the location of metastases. Read more about diagnostic tests here.

Doctors will use later tests to see how well your treatment is working, if it is shrinking the cancer or keeping it from growing. Additionally, doctors will ask about your symptoms—treatment should also manage pain, other symptoms and treatment side-effects.

A lot of the valuable information will come from your pathology report. This in-depth description of your cancer may seem intimidating because of all the medical terminology. To better understand it, please visit our pathology page. Also, remember that a metastatic recurrence may not have the same pathology as your original cancer. Talk to your doctor about this possibility and discuss having another biopsy to learn more about your new pathology**.

Lines of Treatment

Understanding what to expect during your treatment can make it feel more manageable. In general, doctors will try one therapy after another, pursuing each one as long as it works. If one course of therapy stops working, you can turn to others to stabilize the disease. Doctors refer to each new treatment as a “line of treatment.”

By closely monitoring treatments and changing them when necessary, doctors can often stabilize your cancer for a long time. For this reason, some doctors view treating metastatic breast cancer as similar to treating a chronic disease.

Clinical Trials

Be sure to ask your doctor if you might qualify for any clinical trials. For metastatic women, trials should be considered as a first resort, not a last one. Some clinical trials may not allow women with a lot of pre-treatment to enroll. Talk to your doctor about your eligibility.

These trials, important sources of information for researchers, also give you the opportunity to try new treatments. They may offer an improvement over the current, standard treatments. One doctor may have access to clinical trials that another doesn’t, so look around. Learn more about clinical trials.

RSS: Metastatic Breast Cancer Clinical Trials

Studies found on ClinicalTrials.gov by a search of: metastatic breast cancer | updated in the last 30 days


Efficacy and Tolerability of Eribulin Plus Lapatinib in Patients With Metastatic Breast Cancer (E-VITA)
Condition:   Metastatic Breast Cancer
Interventions:   Drug: Lapatinib + 1,23 mg Eribulin;   Drug: Lapatinib + 1,76 mg Eribulin
Sponsors:   German Breast Group;   German Breast Group
Recruiting - verified February 2012

Wed, 08 Feb 2012 12:00:00 EST

The Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide or In Combination With Carboplatin and Paclitaxel Versus Placebo in Subjects With BRCA1 and BRCA2 Mutation and Metastatic Breast Cancer.
Condition:   Metastatic Breast Cancer
Interventions:   Drug: Veliparib;   Drug: Temozolomide;   Drug: Carboplatin;   Drug: Paclitaxel;   Drug: Placebo
Sponsors:   Abbott;   Abbott
Recruiting - verified March 2012

Fri, 06 Jan 2012 12:00:00 EST

Pazopanib in Combination With Capecitabine in Patients With Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Intervention:   Drug: Pazopanib plus capecitabine
Sponsors:   German Breast Group;   German Breast Group
Active, not recruiting - verified December 2011

Wed, 21 Dec 2011 12:00:00 EST

A Study Evaluating the Efficacy and Safety of Lapatinib + Vinorelbine in ErbB2 Positive Metastatic Breast Cancer Patients
Condition:   Metastatic Breast Cancer
Intervention:   Drug: Lapatinib, Vinorelbine
Sponsors:   Central European Cooperative Oncology Group;   Central European Cooperative Oncology Group
Recruiting - verified April 2012

Thu, 27 May 2010 12:00:00 EDT

Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer
Conditions:   HER2/Neu Over-expressing Locally Advanced Breast Cancer;   Metastatic Breast Cancer
Interventions:   Drug: everolimus, vinorelbine, trastuzumab;   Drug: Placebo + vinorelbine + trastuzumab
Sponsors:   Novartis;   Novartis Pharmaceuticals
Recruiting - verified May 2012

Mon, 02 Nov 2009 12:00:00 EST

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer.
Conditions:   Metastatic Breast Cancer;   Metastases, Brain
Interventions:   Drug: capecitabine;   Drug: lapatinib;   Drug: trastuzumab
Sponsors:   GlaxoSmithKline;   GlaxoSmithKline
Recruiting - verified April 2012

Thu, 08 Jan 2009 12:00:00 EST

Phase Ⅱ Clinical Study of R435 (Bevacizumab) in Combination With Paclitaxel in Patients With Inoperable Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Interventions:   Drug: bevacizumab;   Drug: Paclitaxel
Sponsors:   Chugai Pharmaceutical;   Chugai Pharmaceutical
Completed - verified April 2012

Thu, 26 Apr 2007 12:00:00 EDT

Spousal Relationships and Pain in Metastatic Breast Cancer
Condition:   Breast Cancer
Interventions:   Behavioral: Questionnaire;   Behavioral: Interview
Sponsors:   M.D. Anderson Cancer Center;   M.D. Anderson Cancer Center;   Department of Defense
Recruiting - verified May 2012

Mon, 09 Oct 2006 12:00:00 EDT

A Phase II Trial of Abraxane™ Given Weekly as a Single Agent in First-line Treatment of Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer
Intervention:   Drug: Paclitaxel Albumin Nanoparticle for Injectable Suspension
Sponsors:   Veeda Oncology;   Veeda Oncology;   Celgene Corporation
Completed - verified May 2012

Tue, 08 Nov 2005 12:00:00 EST

GW572016 For Treatment Of Refractory Metastatic Breast Cancer
Conditions:   Metastatic Breast Cancer;   Neoplasms, Breast
Intervention:   Drug: GW572016
Sponsors:   GlaxoSmithKline;   GlaxoSmithKline
Completed - verified April 2012

Wed, 11 Jun 2003 12:00:00 EDT

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